Niacinamide is a key ingredient to treat age-related skin changes, acne, and skin discoloration. It naturally calms the skin and provides dramatic skin brightening for a wide variety of skin types. It can help with almost any minor skin concern, whether you're looking to treat acne or just add a little more brightness to your complexion. Niacinamide is generally considered to be such a soothing ingredient that there are very few instances of irritation even with the use of high percentages. Start out with a product that has at least a 4% niacinamide concentration.